説明
Krebs Cycle Accelerator⁴⁰ — The Most Complete VO2 Max Supplement Ever Built for Athletes
One sachet. Forty full-dose actives. Eight synergistic systems working in the same 30 minutes to raise your oxygen delivery, accelerate ATP production, buffer fatigue and hold your power when everyone else fades. This is not a pre-workout. This is a VO2 max supplement engineered by SCN™ for athletes who refuse to leave anything on the table.
Choose your sport — one formula, every athlete
🏃 Endurance Athletes
Runners, cyclists, triathletes, swimmers, rowers: more oxygen to the working muscle, faster Krebs cycle turnover, lower heart-rate drift and a stronger finish. The VO2 max supplement built for your discipline.
🏋️ Strength & Power Athletes
Lifters, sprinters, throwers, CrossFit: 9 g of three creatines plus D-ribose, betaine and ubiquinol for explosive ATP-PCr power, more quality reps and faster between-set recovery.
⚽ Team & Combat Sports
Football, basketball, rugby, MMA, tennis: repeated-sprint capacity, sharper reaction time, CNS focus and ammonia clearance for the last ten minutes when matches are decided.
🧠 Masters, Health & Longevity
Athletes 35+ and active professionals: ubiquinol, R-ALA, Senactiv®, adaptogens and full B-complex support mitochondrial function, cellular energy and mental sharpness — training hard, ageing well.
Why Every Serious Athlete Needs a VO2 Max Supplement
VO2 max — the maximum rate at which your body can take in, transport and use oxygen — is the single best laboratory predictor of endurance performance and one of the strongest predictors of long-term health. Every watt you push, every stride you hold, every rep you grind through is limited by how fast oxygen reaches your mitochondria and how fast those mitochondria turn fuel into ATP through the Krebs cycle.
Most “pre-workouts” give you caffeine and a tingle. Most VO2 max supplements give you one ingredient — a nitrate, a beetroot powder, a single adaptogen. SCN™ did something no other brand has done: we mapped every bottleneck between the air you breathe and the power you produce, then addressed each one with a full, research-based dose, all in a single sachet taken 30–40 minutes before your warm-up.
- Supports VO2 max and oxygen uptake
- Improves blood flow & oxygen transport to muscle
- Supports lung and respiratory function
- Helps keep a lower overall heart-rate curve
- Improves heart-rate recovery between efforts
- Accelerates ATP-PCr resynthesis
- Activates mitochondrial function
- Speeds up Krebs cycle reactions
- Supplies the substrates the Krebs cycle needs
- Supports glycolysis and glycogen sparing
- Raises nitric oxide levels
- Supports healthy testosterone levels during training
- Supports hormone synthesis during & after training
- Improves power & strength output
- Improves reaction time
- More sets & reps before failure
- Improves recovery
- Improves mood & mental concentration
- Improves CNS–muscle coordination
- Supports balance & kinaesthesia
- Reduces excess post-exercise ammonia
- Reduces post-exercise fatigue
40 supplements. 1 sachet. 0 compromises.
Buy one Krebs Cycle Accelerator⁴⁰ and you are buying 40 full-dose products, years of athlete trials and the most advanced VO2 max supplement on the market.
Add Krebs Cycle Accelerator⁴⁰ to basket →
Multi-buy: 2 pieces −8% · 3 pieces −12% · buy 5 get +1 FREE
8 Synergistic Systems — How the 40 Ingredients Work Together
A formula is not a list of ingredients; it is a set of relationships. Below is exactly how the actives in Krebs Cycle Accelerator⁴⁰ amplify each other. Click each system to see the synergy.
System 1 — Oxygen Delivery & Nitric Oxide Synergy
The problem: your muscles can only use the oxygen that reaches them. Vasoconstriction, low nitric oxide (NO) and oxidative breakdown of NO all limit oxygen transport before VO2 max is ever tested.
The synergy: Krebs Cycle Accelerator⁴⁰ attacks NO from both biochemical pathways at once. 硝酸クレアチン supplies inorganic nitrate for the nitrate → nitrite → NO pathway (oxygen-independent — exactly the pathway that matters in hypoxic, hard-working muscle). Citrulline and arginine-AKG drive the L-arginine → NO synthase pathway; citrulline is used because it bypasses liver breakdown and raises plasma arginine more effectively than arginine itself. Then grape seed and maritime pine proanthocyanidins protect that NO from being destroyed by superoxide and up-regulate endothelial NO synthase, while vitamin C recycles the antioxidants and preserves endothelial function. タウリン adds vasodilation and membrane stabilisation.
The result for you: more oxygen and nutrients per heartbeat, lower oxygen cost at the same pace, a lower heart-rate curve and a visibly better pump — the foundation of a true VO2 max supplement.
System 2 — ATP-PCr Explosive Power Synergy
The problem: every sprint, surge, lift and attack runs on phosphocreatine. When PCr runs out in 8–10 seconds, power collapses until it is resynthesised.
The synergy: 9 g of three creatines saturate muscle phosphocreatine without a loading phase and without the water weight endurance athletes hate — HCl for solubility and speed, nitrate for the dual creatine + NO action, Creapure® for the most-studied, purest monohydrate on earth. Betaine (TMG) donates methyl groups so your body also makes more creatine endogenously and acts as an osmolyte that protects cells under heat and stress. D-ribose is the backbone of the adenine nucleotide — it rebuilds the ATP pool itself after very intense efforts. Phosphate and magnesium are the literal co-factors of the creatine kinase reaction (Mg-ATP). ユビキノール keeps the electron transport chain running so the aerobic engine refills PCr faster between efforts.
The result for you: higher peak power, more repeated sprints at the same output, more reps before set-stop, faster recovery between intervals.
System 3 — Krebs Cycle & Mitochondrial Fuel Synergy
The problem: oxygen is useless if the Krebs cycle cannot turn fuel into NADH/FADH₂ fast enough to feed the electron transport chain. Most athletes are rate-limited here without knowing it.
The synergy: this is the system that gives the product its name. Pyruvate is the direct entry substrate — it becomes acetyl-CoA (via pyruvate dehydrogenase) and oxaloacetate (via pyruvate carboxylase), topping up both halves of the cycle. The enzymes that do this are dependent on thiamine (B1, as TPP) そして R-alpha-lipoic acid — both supplied in full doses, so pyruvate is not just given but processed. Riboflavin (FAD), niacin (NAD⁺) そして pantothenic acid (coenzyme A) are the three cofactors every turn of the cycle consumes. L-carnitine shuttles fatty acids into the mitochondria to provide a second, glycogen-sparing fuel stream. ユビキノール is the electron carrier between Complex I/II and Complex III — the final hand-off that produces ATP. Cordyceps supports oxygen utilisation and ATP generation.
The result for you: faster aerobic energy turnover, less reliance on glycogen, less lactate at the same intensity, and a higher sustainable pace — VO2 max turned into real-world power.
System 4 — Acid Buffering & Anti-Fatigue Synergy
The problem: hydrogen-ion accumulation, central fatigue and perceived exertion stop you long before your muscles are truly empty.
The synergy: β-アラニン raises muscle carnosine, the primary intracellular pH buffer for 1–10 minute efforts. リン酸塩 adds extracellular buffering and supports 2,3-DPG so haemoglobin releases oxygen more readily to muscle. タウリン regulates calcium handling in the muscle fibre, so contraction quality holds as fatigue sets in. Then the adaptogen trio — Rhodiola, Cordyceps and Panax ginseng — lowers perceived exertion and heart rate at a given workload while supporting oxygen utilisation. A deliberately low 30 mg of カフェイン paired with glucuronolactone gives alertness and glycogen sparing without jitters, heart-rate spikes or sleep disruption — crucial for athletes who train in the evening or compete in multiple sessions.
The result for you: the burn arrives later, the “I can’t” arrives much later, and you hold your pace through the final third.
System 5 — Ammonia Clearance & Recovery Synergy
The problem: long or intense exercise produces ammonia from amino-acid breakdown and AMP deamination. Ammonia is neurotoxic, impairs the Krebs cycle and is a major driver of “heavy legs” and mental fog late in a session.
The synergy: citrulline, ornithine and arginine are the three intermediates of the urea cycle — supplying all three at once lets the liver convert ammonia to urea faster than supplying any one alone. The alpha-ketoglutarate (AKG) salt form is deliberate: AKG is itself a Krebs cycle intermediate そして an ammonia acceptor (forming glutamate), so it detoxifies ammonia right inside the muscle while refilling the cycle. Methionine, betaine, B6 and B12 run the methylation cycle that regenerates these pathways and keeps homocysteine in check. セナクティブ accelerates post-exercise glycogen replenishment and muscle-cell regeneration by clearing senescent cells.
The result for you: less post-exercise ammonia, clearer head in the final kilometres, lower muscle damage markers and a faster return to training the next day.
System 6 — Hormonal & Anabolic Drive Synergy
The problem: hard training temporarily suppresses testosterone and raises cortisol. Over weeks, that blunts strength, recovery, libido and drive.
The synergy: D-aspartic acid acts at the hypothalamus and pituitary to support luteinising-hormone signalling. テストフェン — the clinically studied fenugreek extract standardised to 50% Fenuside™ — supports free testosterone within the normal range, anabolic activity and glycogen resynthesis. Magnesium and B6 are cofactors in steroid hormone synthesis and reduce testosterone binding to SHBG; pantothenic acid is required for steroid hormone and adrenal function. Cinnamon and inositol support insulin sensitivity so the post-training nutrient window actually delivers nutrients into muscle. コリン supports acetylcholine for the neuromuscular drive that makes hormonal signalling count.
The result for you: hormonal support during the training block itself, better anabolic response to the work you do, and better adaptation session after session.
System 7 — Brain, Focus & CNS-Muscle Coordination Synergy
The problem: performance is neurological before it is muscular. Reaction time, motor-unit recruitment, balance and decision-making all drop as the CNS fatigues.
The synergy: DMAE and choline are both acetylcholine precursors — the neurotransmitter of every muscle contraction and of attention. Giving two precursors with different kinetics sustains acetylcholine through the whole session. Rhodiola and ginseng modulate dopamine, serotonin and cortisol for calm, durable focus. Caffeine + glucuronolactone + taurine is the classic, research-tested trio for reaction time, concentration and memory — dosed here for sharpness, not stimulation. B1, B2, B3, B5, B6 and B12 are the cofactors for neurotransmitter synthesis and nerve function. Maritime pine OPCs support cerebral blood flow.
The result for you: faster reactions, cleaner technique under fatigue, better pacing decisions and the mental edge in the moments that decide results.
System 8 — Bioavailability & Antioxidant Recycling Synergy
The problem: 40 ingredients mean nothing if they are not absorbed — and hard exercise produces reactive oxygen species that oxidise your NO, your CoQ10 and your membranes.
The synergy: BioPerine® (95% piperine) inhibits intestinal and hepatic metabolism and increases the absorption of vitamins C and B6, CoQ10, curcuminoids and many botanicals — so every other ingredient on this label works harder. Then the antioxidant network recycles itself: R-ALA regenerates both vitamin C そして ubiquinol from their oxidised forms; vitamin C regenerates vitamin E; OPCs from grape seed and pine protect vitamin C and NO. タウリン stabilises mitochondrial membranes so the whole system keeps producing ATP under oxidative load.
The result for you: you absorb what you paid for, your nitric oxide survives longer, and your mitochondria are protected exactly when they are working hardest.
The Research Behind the Formula
SCN™ builds formulas on published science and real-athlete trials. The key actives in Krebs Cycle Accelerator⁴⁰ are among the best-studied performance ingredients in the world:
This is what “research-based” actually looks like.
No pixie dusting. No proprietary blends hiding 50 mg doses. Every ingredient is on the label at a dose that matters.
Krebs Cycle Accelerator⁴⁰ vs. a Typical “VO2 Max Supplement”
| Feature | Typical nitrate / pre-workout product | SCN™ Krebs Cycle Accelerator⁴⁰ |
|---|---|---|
| Nitric-oxide pathways targeted | One (nitrate or citrulline) | Both — nitrate + citrulline/arginine, protected by OPCs |
| Creatine | Usually none, or 3 g monohydrate | 9 g — HCl + Nitrate + Creapure® |
| Krebs cycle substrates & cofactors | None | Pyruvate + B1/B2/B3/B5 + R-ALA + carnitine |
| Active CoQ10 (ubiquinol) | None | 400 mg Kaneka Ubiquinol™ |
| Ammonia clearance | None | Citrulline + ornithine-AKG + arginine-AKG |
| Adaptogens | Maybe one | Rhodiola + Cordyceps + Panax ginseng + Senactiv® |
| Hormonal support | None | D-aspartic acid + Testofen® + Mg + B6 |
| Stimulant load | 200–400 mg caffeine | 30 mg — evening-training and competition friendly |
| Bioavailability enhancer | Rarely | BioPerine® 20 mg |
| Doping safety | Varies | 100% doping-free, cross-contamination safe |
Complete Ingredient Breakdown — All 40 Actives, Nothing Hidden
Nutrients per recommended daily dose (1 sachet / 22.5 g):
| 原材料 | 1袋あたり |
|---|---|
| クレアチン塩酸塩 | 4000 mg |
| 硝酸クレアチン | 4000 mg |
| ピルビン酸カルシウム | 1400 mg |
| of which pyruvic acid | 910 mg |
| of which calcium | 217 mg (27% NRV) |
| Creapure® creatine monohydrate | 1000 mg |
| グルクロノラクトン | 1000 mg |
| DMAE (dimethylaminoethanol) | 750 mg |
| ベタイン塩酸塩 | 500 mg |
| Ubiquinol Kaneka™ (reduced coenzyme Q10) | 400 mg |
| L-Citrulline DL-malate | 400 mg |
| L-カルニチン酒石酸塩 | 300 mg |
| D-アスパラギン酸 | 300 mg |
| ビタミンC | 300 mg (375% NRV) |
| ブドウ・エキスヴィティス・ヴィニフェラ L.), 95% proanthocyanidins | 300 mg (285 mg OPC) |
| L-シトルリン | 250 mg |
| L-Arginine alpha-ketoglutarate | 250 mg |
| β-アラニン | 250 mg |
| 第二リン酸ナトリウム | 250 mg (sodium 80.97 mg · phosphate 52.5 mg) |
| ロディオラエキスロディオラ・ロゼア L.), 6% rosavins | 250 mg (15 mg rosavins) |
| イノシトール | 250 mg |
| L-タウリン | 250 mg |
| 冬虫夏草エキス(冬虫夏草), 7% polysaccharides | 250 mg (17.5 mg) |
| D-リボース | 250 mg |
| Choline bitartrate, 40% choline | 250 mg (100 mg choline) |
| 海松エキスマツ属 Lamb), 95% proanthocyanidins | 200 mg (190 mg OPC) |
| クエン酸マグネシウム | 190 mg (30 mg Mg · 8% NRV) |
| L-メチオニン | 150 mg |
| L-Ornithine alpha-ketoglutarate | 150 mg |
| Testofen® fenugreek extract (トリゴネラ・ホエナム・グラエカム L.), 50% saponins | 150 mg (75 mg) |
| シナモン・エキス桂皮 ブルーメ) | 100 mg |
| Senactiv® (三七人参 & Rosa extracts) | 100 mg |
| 高麗人参エキス田七人参 C.A. Mey.), 30% ginsenosides | 100 mg (30 mg) |
| ナイアシン | 70 mg NE (437.5% NRV) |
| 無水カフェイン | 30 mg |
| R-ALA (R-alpha-lipoic acid) | 30 mg |
| BioPerine® black pepper extract (黒胡椒 L.) | 20 mg |
| Vitamin B1 (thiamine) | 15.8 mg (1436% NRV) |
| Pantothenic acid (B5) | 13.87 mg (231% NRV) |
| ビタミンB6 | 12 mg (857% NRV) |
| Vitamin B2 (riboflavin) | 10 mg (714% NRV) |
| ビタミンB12 | 25 µg (1000% NRV) |
NRV = Nutrient Reference Value.
Creatine Complex — 9 g of Three Creatines
クレアチン塩酸塩 · 4000 mg
Creatine bound to hydrochloride is dramatically more water-soluble than monohydrate, which means faster dissolution, faster uptake and excellent tolerance at high doses with no bloating. Because it is absorbed so efficiently, it works from day one — no loading phase, no off phase. Creatine HCl is the engine of the no-water-retention design that lets endurance athletes enjoy full creatine power without extra body weight.
硝酸クレアチン · 4000 mg
A 2-in-1 molecule: in the body it splits into creatine and inorganic nitrate, each absorbed separately. You get the phosphocreatine power of creatine and the nitric-oxide, oxygen-delivery and mitochondrial-efficiency benefits of nitrate from one ingredient. Studies over 28 days confirmed safety and showed improvements in lifting volume, peak power and velocity — in other words, more work, more power, more speed. Explosive endurance.
Creapure® Creatine Monohydrate · 1000 mg
Creapure® is the gold-standard creatine monohydrate manufactured by AlzChem in Trostberg, Germany — the most widely studied form of creatine on earth, IFS Food certified, vegan, kosher and halal, and tested to exclude impurities like dicyandiamide and dihydrotriazine. Creatine raises phosphocreatine stores so ATP is regenerated faster during repeated high-intensity efforts, supporting strength, ballistic power, sprint ability, muscle endurance, fatigue resistance, lean mass and recovery — in every sport, at every level, and increasingly recognised for brain performance and healthy ageing.
Nitric Oxide & Blood Flow Complex
L-シトルリンDL-リンゴ酸塩 · 400 mg & L-Citrulline · 250 mg
Citrulline is the most efficient way to raise plasma arginine and nitric oxide because, unlike arginine, it bypasses first-pass metabolism in the gut and liver. It is also a core urea-cycle intermediate that removes ammonia. The malate salt adds a Krebs cycle intermediate (malate → oxaloacetate) for aerobic ATP production, while free-form citrulline delivers a fast, pure dose. Research links citrulline to more repetitions before failure, reduced perceived exertion and less muscle soreness 24–48 hours after training. It also supports muscle protein synthesis signalling and the post-exercise growth hormone response.
L-アルギニンα-ケトグルタル酸塩 · 250 mg
Arginine is the direct substrate for nitric oxide synthase. Bound to alpha-ketoglutarate it does double duty: AKG is a Krebs cycle intermediate and a powerful ammonia scavenger (forming glutamate and glutamine), so it supports both vasodilation and detoxification during long efforts.
Grape Seed Extract 95% Proanthocyanidins · 300 mg
Oligomeric proanthocyanidins (OPCs) are among the most potent plant antioxidants. They protect nitric oxide from oxidative destruction, support endothelial function and blood flow, reduce oxidative damage from hard training, and support collagen and connective tissue integrity. Standardised to 95% so every milligram counts.
Maritime Pine Extract 95% Proanthocyanidins · 200 mg
Pine bark OPCs complement grape seed with a different OPC profile. Research on pine bark extract in athletes points to improved endurance and reduced muscle fatigue through lower oxidative stress and inflammation, better circulation, and improved concentration and mood via enhanced cerebral blood flow. Pine bark OPCs also improve the recycling of vitamins C and E.
ビタミンC · 300 mg (375% NRV)
Essential for collagen formation in blood vessels, cartilage, tendon and bone, for iron absorption and for protecting cells from oxidative stress. In this formula vitamin C also protects nitric oxide and regenerates vitamin E, and contributes to normal energy-yielding metabolism and to the reduction of tiredness and fatigue.
Endurance Maximising Complex
ピルビン酸カルシウム · 1400 mg (910 mg pyruvic acid)
Pyruvate is the end product of glycolysis and the entry point of the Krebs cycle. It feeds the cycle via acetyl-CoA, replenishes oxaloacetate, participates in the glucose–alanine cycle and the pyruvate–lactate equilibrium, and supports fat oxidation. For athletes that means sustained energy, glycogen sparing, improved endurance, support for lean-muscle maintenance and reduced fatigue — delivered as calcium pyruvate for stability and an additional 27% NRV of calcium for muscle contraction.
Beta-Alanine · 250 mg
The rate-limiting precursor of muscle carnosine, the fibre’s main intracellular pH buffer. Higher carnosine delays the acidosis that forces you to slow down in efforts lasting 30 seconds to 10 minutes. Meta-analyses confirm improved exercise capacity, more work completed and later time to exhaustion. Beta-alanine supports anaerobic endurance, aerobic endurance, pH stability during training and the ability to train harder and longer.
Kaneka Ubiquinol™ · 400 mg
Ubiquinol is the reduced, active form of coenzyme Q10 — the form your body actually uses in the electron transport chain to make ATP, and the body’s major fat-soluble antioxidant. It is far better absorbed than conventional ubiquinone, so a lower dose achieves a higher plasma level. In the Olympic-athlete trial, 300 mg daily for 6 weeks increased power per kg significantly more than placebo; SCN™ delivers 400 mg. Ubiquinol supports cellular energy production, peak power, aerobic and anaerobic capacity, mental alertness, CNS coordination and reduced post-exercise creatine kinase. Intensive training and ageing both deplete CoQ10 — this restores it.
グルクロノラクトン · 1000 mg
A natural glucose metabolite in equilibrium with glucuronic acid. Research links glucuronolactone to inhibition of fatiguing exercise by-products and, in combination with caffeine and taurine, to improved aerobic and anaerobic performance, more total repetitions, better reaction time, concentration and memory. It has a well-documented synergy with citrulline and caffeine and supports liver detoxification pathways (glucuronidation).
Anhydrous Caffeine · 30 mg
Deliberately micro-dosed. Caffeine mobilises fat for fuel, spares glycogen, lowers perceived exertion and sharpens the CNS. At 30 mg — roughly a third of an espresso — Krebs Cycle Accelerator⁴⁰ gives you the alertness and glycogen-sparing signal without heart-rate elevation, jitters or sleep disruption, so you can take it before evening sessions or stack it with your own caffeine strategy on race day. Fully competition-legal.
D-リボース · 250 mg
The five-carbon sugar that forms the backbone of ATP, ADP and AMP. After very intense exercise the total adenine nucleotide pool is depleted and can take days to rebuild; ribose shortens that process. Supports ATP resynthesis, muscle power and strength, tolerance to high-intensity exercise, recovery and endurance.
Betaine HCl (Trimethylglycine) · 500 mg
A methyl donor and osmolyte from beetroot. Betaine supports endogenous creatine synthesis, protects cells from heat and osmotic stress, supports homocysteine metabolism and SAMe production (mood, sleep, cognition). Research shows improved strength, power, squat repetitions and anaerobic sprint power, plus support for lean body mass. “Just train longer.”
Cordyceps sinensis Extract 7% Polysaccharides · 250 mg
The legendary high-altitude fungus of Tibetan medicine, used by endurance athletes for oxygen utilisation. Cordyceps supports ATP production, oxygen uptake and blood oxygen levels, respiratory function and immune resilience. Trials with Cordyceps-containing blends show improved VO2 max, ventilatory threshold and time to exhaustion.
L-Ornithine Alpha-Ketoglutarate · 150 mg
Ornithine is the central amino acid of the urea cycle (the “ornithine cycle”) — it is what converts toxic ammonia into urea for excretion. Ornithine is also converted to arginine (nitric oxide, creatine synthesis) and supports growth-hormone release. Research shows less exercise-induced fatigue and more efficient cellular energy use with ornithine supplementation. The AKG salt adds a Krebs cycle intermediate and a second ammonia-trapping mechanism.
L-メチオニン · 150 mg
An essential sulphur amino acid and the precursor of SAMe, the body’s universal methyl donor — needed for creatine synthesis, carnitine synthesis and neurotransmitter production. Methionine completes the methylation cycle together with betaine, B6 and B12.
糖代謝・脂質代謝剤
L-カルニチン酒石酸塩 · 300 mg
Carnitine transports long-chain fatty acids into the mitochondria for beta-oxidation — turning fat into ATP, sparing glycogen and reducing amino-acid breakdown. For athletes it supports sustained energy, blood flow, lower markers of metabolic stress, reduced muscle soreness and faster recovery. Tartrate is the fast-acting form preferred in sports nutrition.
Rhodiola rosea Extract 6% Rosavins · 250 mg (15 mg rosavins)
The premier adaptogen for athletes. Rhodiola contains over 140 compounds including rosavins and salidroside, with anti-fatigue, nootropic, mood-supporting and CNS-protective effects. Acute Rhodiola before exercise increases time to exhaustion, lowers heart rate at submaximal intensity, reduces perceived exertion, improves time-trial performance and reduces post-exercise lactate and creatine kinase. Taken 30–45 minutes before the main part of training, it makes hard work feel easier.
イノシトール · 250 mg
A vitamin-like compound (formerly vitamin B8) concentrated in the brain, where it is a second messenger for serotonin, insulin and other signalling. Inositol supports insulin sensitivity and glucose handling, hormonal balance, mood and circulation.
Choline Bitartrate 40% · 250 mg (100 mg choline)
Choline is the direct precursor of acetylcholine — the neurotransmitter of every muscle contraction and of focus — and plasma choline falls during prolonged exercise. It is also lipotropic: it mobilises fat from the liver, forms betaine as a methyl donor and builds cell membranes (phosphatidylcholine). Sub-optimal choline is associated with muscle and liver stress.
Cinnamon Extract (桂皮) · 100 mg
True Ceylon cinnamon, rich in polyphenols. Supports insulin sensitivity and glucose metabolism so carbohydrate reaches the muscle efficiently, supports fat metabolism and energy production, supports blood-vessel dilation and provides antioxidant and anti-inflammatory activity after hard sessions.
DMAE（ジメチルアミノエタノール） · 750 mg
A choline analogue that crosses the blood–brain barrier readily and supports acetylcholine production with different kinetics from choline bitartrate — together they sustain neuromuscular drive through the whole session. DMAE supports focus, alertness, mood and the mind–muscle connection, and has membrane-protective antioxidant activity.
ホルモン＆テストステロンサポート・コンプレックス
D-アスパラギン酸 · 300 mg
An amino acid that acts in the hypothalamus and pituitary to support the release of luteinising hormone, the signal for natural testosterone production in the testes. Healthy testosterone during a training block supports protein synthesis, repair of damaged fibres, lean-mass gain, fat metabolism, strength and drive.
Testofen® Fenugreek Extract 50% Saponins · 150 mg (75 mg)
Gencor’s patented トリゴネラ・ホエナム・グラエカム extract standardised to Fenuside™ saponin glycosides. In a randomised, double-blind, placebo-controlled trial of 60 resistance-training men, Testofen® significantly supported free testosterone, showed anabolic activity (reduced BUN), supported creatine uptake in muscle (serum creatinine), immune function and body-fat reduction. In a 12-week trial of 120 men aged 40–75, Testofen® reduced age-related androgen-decline symptoms and increased free and total testosterone. Fenugreek also acts as an insulin mimetic, supporting glucose disposal and glycogen resynthesis after training.
Magnesium Citrate · 190 mg (30 mg Mg)
Magnesium is the cofactor for every ATP-dependent reaction (Mg-ATP), contributes to normal muscle and nerve function, electrolyte balance, protein synthesis, reduction of tiredness and fatigue, and psychological function, and supports healthy testosterone levels in active men. Citrate is highly absorbable and gentle on the stomach.
Performance Vitamin & Mineral Complex
Vitamin B1 — Thiamine · 15.8 mg (1436% NRV)
As thiamine pyrophosphate, B1 is the essential coenzyme for pyruvate dehydrogenase (pyruvate → acetyl-CoA) and alpha-ketoglutarate dehydrogenase (AKG → succinyl-CoA) — the two gate-keeping reactions of the Krebs cycle. Without thiamine the pyruvate in this formula cannot enter the cycle. Contributes to normal energy-yielding metabolism, heart function, nervous system and psychological function.
Vitamin B2 — Riboflavin · 10 mg (714% NRV)
As FAD, riboflavin carries electrons in the Krebs cycle (succinate dehydrogenase) and in beta-oxidation. Contributes to normal energy-yielding metabolism, iron metabolism, red blood cells, protection of cells from oxidative stress, nervous system function and reduction of tiredness and fatigue.
Niacin — Vitamin B3 · 70 mg NE (437.5% NRV)
The precursor of NAD⁺ and NADP⁺, used by over 200 enzymes — including three NAD⁺-dependent dehydrogenases in every turn of the Krebs cycle. Contributes to normal energy-yielding metabolism, psychological function, nervous system function and reduction of tiredness and fatigue.
Pantothenic Acid — Vitamin B5 · 13.87 mg (231% NRV)
The core of coenzyme A — the molecule that carries acetyl groups into the Krebs cycle and fatty acids into beta-oxidation. Contributes to normal energy-yielding metabolism, mental performance, synthesis and metabolism of steroid hormones and neurotransmitters, and reduction of tiredness and fatigue. Supports adrenal function under training stress.
ビタミンB6 · 12 mg (857% NRV)
As pyridoxal-5-phosphate, B6 is the cofactor for glycogen phosphorylase (releasing glucose from muscle glycogen), amino-acid metabolism and neurotransmitter synthesis (dopamine, serotonin, GABA). Contributes to normal energy-yielding metabolism, protein and glycogen metabolism, red blood cell formation, immune function, regulation of hormonal activity, homocysteine metabolism and reduction of tiredness and fatigue.
ビタミンB12 · 25 µg (1000% NRV)
Essential for red blood cell formation (oxygen transport), nerve function, homocysteine metabolism, energy-yielding metabolism and psychological function. Together with B6, methionine and betaine it completes the methylation cycle that regenerates creatine, carnitine and neurotransmitters.
Sodium Diphosphate · 250 mg (sodium 80.97 mg · phosphate 52.5 mg)
Phosphate is the “P” in ATP and phosphocreatine. Phosphate loading supports extracellular buffering and 2,3-DPG in red blood cells, which helps haemoglobin release oxygen to working muscle. The small sodium content supports fluid balance and absorption.
Antioxidant & Mitochondrial Support
R-Alpha-Lipoic Acid · 30 mg
The natural R-isomer of the “universal antioxidant” — active in both water and fat compartments, inside and outside the cell. R-ALA is an essential cofactor of the pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes (the same Krebs gate-keepers as thiamine), regenerates vitamins C and E and ubiquinol, supports glucose and fat metabolism and insulin sensitivity, protects mitochondria from the reactive oxygen species they produce under load, and has anti-inflammatory action supporting muscle regeneration after exercise.
L-タウリン · 250 mg
Not a stimulant — a sulphur amino acid that regulates calcium handling in muscle fibres, stabilises cell membranes, acts as an osmolyte for hydration and electrolyte balance, supports CNS and eye function, insulin sensitivity and antioxidant defence. Meta-analysis shows a single dose improves endurance performance and time to exhaustion, and taurine reduces exercise-induced muscle damage and speeds recovery.
Panax ginseng Extract 30% Ginsenosides · 100 mg (30 mg)
Korean ginseng standardised to 30% ginsenosides — the active saponins. Ginseng is an adaptogen that increases resilience to physical and mental stress, supports memory, concentration and reaction under fatigue, and has anti-inflammatory ginsenosides. Systematic review supports improved exercise endurance with Panax ginseng.
Bioavailability & Regeneration Enhancers
Senactiv® — 三七人参 & Rosa Extracts · 100 mg
The first senolytic sportsceutical. Senactiv® activates macrophages to clear senescent (“zombie”) cells from exercised muscle and allows stem cells to migrate in and regenerate new muscle and blood-vessel cells. Younger cells have more mitochondria, higher ATP capacity and more glycogen storage. NuLiv Science’s clinical programme reports increased high-intensity endurance, markedly faster glycogen replenishment, lower inflammation markers (TNF-α, IL-6, CK), reduced lipid peroxidation and increased citrate synthase activity (a marker of mitochondrial density).
BioPerine® Black Pepper Extract 95% Piperine · 20 mg
The patented, clinically validated bioavailability enhancer. Piperine increases nutrient absorption by stimulating the gut’s absorptive surface and inhibiting the enzymes that break down nutrients in the gut wall and liver — it is documented to increase absorption of vitamin C, vitamin B6, coenzyme Q10, beta-carotene, selenium, curcuminoids and many botanicals. BioPerine® also has a mild thermogenic effect and supports dopamine and serotonin signalling, memory, attention and motivation. In a 40-ingredient formula, it is the ingredient that makes the other 39 count.
How to Use Krebs Cycle Accelerator⁴⁰
Stack it: pair with バイカルブ・ライツ¹⁰ゼロ for extracellular buffering (the beta-alanine + bicarbonate combination shows the largest effect in meta-analysis), with intrAMINO X12 during the session, and with Anticatabolic Activa.Tor 9 after.
Storage note: supplements with a high concentration of actives and no preservatives are humidity-sensitive and may clump. Keep cool and dry, reseal well, use within 30 days of opening, never use wet hands or tools.
100% Doping-Free & Cross-Contamination Safe
Krebs Cycle Accelerator⁴⁰, like every SCN™ product, is 100% doping-free and safe for competing athletes in every sport, worldwide. SCN™ does not use, store, process or handle any substance on the WADA Prohibited List, so there is no risk of cross-contamination. The 30 mg caffeine dose is far below any competition threshold. Your health and your career are the only things that matter to us.
Stop buying 40 tubs. Buy the one that replaces them.
Creatine, nitrate, citrulline, beta-alanine, ubiquinol, rhodiola, cordyceps, taurine, betaine, Testofen®, Senactiv®, full B-complex and 28 more — at full doses, in one sachet, for less than the price of buying three of them separately.
Order Krebs Cycle Accelerator⁴⁰ →
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VO2 Max Supplement — Frequently Asked Questions
What is a VO2 max supplement and does it really work?
A VO2 max supplement is a formula designed to improve how much oxygen your body can deliver to and use in working muscle. Single ingredients with strong evidence include nitrate (73-study meta-analysis showing improved power and time to exhaustion), ubiquinol (+2.5% power in Olympic athletes), Cordyceps (improved VO2 max and ventilatory threshold) and Rhodiola (longer time to exhaustion, lower heart rate). Krebs Cycle Accelerator⁴⁰ combines all of them, plus the Krebs cycle substrates and cofactors that let your mitochondria actually use that oxygen.
How is Krebs Cycle Accelerator⁴⁰ different from a pre-workout?
Pre-workouts are built around high caffeine for a stimulant hit. Krebs Cycle Accelerator⁴⁰ contains only 30 mg caffeine and is built around oxygen delivery, ATP production, acid buffering, ammonia clearance and hormonal support — the physiology that actually determines endurance and repeated power. It is a performance formula, not an energy drink.
Is it only for endurance athletes?
No. The 9 g triple-creatine complex, betaine, D-ribose and phosphate make it a powerful strength and power formula too, and the CNS, reaction-time and ammonia-clearance systems make it ideal for team and combat sports. Endurance athletes get the oxygen and Krebs cycle systems; everyone else gets the same systems applied to repeated sprints and sets.
Will the creatine make me heavier or retain water?
The complex is designed around creatine HCl and creatine nitrate, both highly soluble forms taken without a loading phase, with just 1 g of Creapure® monohydrate. Athletes report the power of creatine without the water weight associated with 20 g/day monohydrate loading protocols.
How long before training should I take it?
30–40 minutes before your warm-up. Nitrate peaks in the blood at 2–3 hours but nitrite and NO effects begin within the hour; Rhodiola, citrulline, caffeine and glucuronolactone peak at 45–60 minutes — so the timing covers your main session.
Can I take it every day?
Yes — all doses are within established safe ranges and the formula contains no banned substances. Most athletes use it on key sessions and competition days (10 sachets = 10 hard days), and use SCN™ Pre-Endurance Training Activator or Nitrate VO2 Maximizer¹⁷ for daily training.
Is Krebs Cycle Accelerator⁴⁰ safe for drug-tested athletes?
Yes. SCN™ is 100% doping-free and cross-contamination safe. We do not handle any WADA-prohibited substance in our facility. The 30 mg caffeine is well below any competition limit.
Can women use it?
Yes. Every performance system — oxygen delivery, creatine, buffering, Krebs cycle cofactors, adaptogens — works identically in women. The hormonal support complex supports healthy hormone synthesis within normal physiological ranges. Not intended for use during pregnancy or breastfeeding.
Why is the caffeine dose so low?
Because stimulation is not the goal. 30 mg provides the glycogen-sparing and alertness signal and the classic caffeine–taurine–glucuronolactone synergy without heart-rate elevation — which would work against the lower-heart-rate benefit of nitrate and Rhodiola — and without disrupting sleep after evening sessions. Add your own caffeine on race day if you want more.
Does it contain anything that could cause a positive test or side effects?
No banned substances. Beta-alanine at 250 mg is far below the tingling (paraesthesia) threshold. Niacin at 70 mg NE may cause a mild, harmless warm flush in sensitive individuals for 15–20 minutes — a sign of vasodilation. Consult your physician if you take medication or have a medical condition.
製品情報 10 sachets × 22.5 g · Red Fruits flavour · 10 servings · SKU SCN65
This website is for your education and general health information only. The ideas, opinions and suggestions contained on this website are not to be used as a substitute for medical advice, diagnosis or treatment from your doctor for any health condition or problem. Food supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Keep out of reach of children. Not intended for use during pregnancy or breastfeeding or by persons under 18. Please consult your physician before starting any supplement if you are taking medication.
