{"id":9236,"date":"2024-06-23T13:36:14","date_gmt":"2024-06-23T10:36:14","guid":{"rendered":"https:\/\/www.s-c-nutrition.com\/?post_type=product&#038;p=9236"},"modified":"2026-10-28T01:42:27","modified_gmt":"2026-10-27T22:42:27","slug":"endurance-pre-workout","status":"publish","type":"product","link":"https:\/\/www.s-c-nutrition.com\/nl\/product\/endurance-pre-workout\/","title":{"rendered":"Endurance Pre-Workout \u2013 Pre-Endurance Training Activator"},"content":{"rendered":"<style>\n.scn-pe{--pink:#e5007e;--pink-soft:#fff0f7;--pink-line:#f7c6de;--ink:#1d1d1f;--muted:#5b5b63;--line:#ececf0;color:var(--ink);font-size:16px;line-height:1.7;max-width:1100px;margin:0 auto}\n.scn-pe *{box-sizing:border-box}\n.scn-pe h2{font-size:clamp(24px,3.2vw,34px);line-height:1.2;margin:56px 0 16px;font-weight:800}\n.scn-pe h2:after{content:\"\";display:block;width:64px;height:4px;background:var(--pink);border-radius:2px;margin-top:14px}\n.scn-pe h3{font-size:22px;line-height:1.3;margin:0 0 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var(--pink);border-radius:14px;padding:22px;background:#fff}\n.scn-pe .pe-card h3{font-size:19px}\n.scn-pe .pe-two{display:grid;grid-template-columns:repeat(auto-fit,minmax(260px,1fr));gap:16px;margin:18px 0 0}\n.scn-pe .pe-two>div{background:var(--pink-soft);border-radius:12px;padding:18px 20px}\n.scn-pe .pe-aud{border:1px solid var(--pink-line);border-radius:16px;padding:26px;margin:18px 0;background:#fff}\n.scn-pe .pe-aud .pe-tag{color:var(--pink);font-weight:800;text-transform:uppercase;letter-spacing:.1em;font-size:13px;margin-bottom:4px;display:block}\n.scn-pe .pe-howto{background:var(--pink-soft);border-left:4px solid var(--pink);border-radius:0 10px 10px 0;padding:12px 16px;margin-top:14px}\n.scn-pe .pe-steps{display:grid;grid-template-columns:repeat(auto-fit,minmax(220px,1fr));gap:14px;margin:20px 0}\n.scn-pe .pe-steps div{background:var(--pink-soft);border-radius:12px;padding:18px}\n.scn-pe .pe-steps b{display:block;font-size:20px;color:var(--pink);margin-bottom:4px}\n.scn-pe 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.pe-ing-head{display:flex;flex-wrap:wrap;justify-content:space-between;gap:8px;margin-bottom:10px;font-size:13px;font-weight:800;text-transform:uppercase;letter-spacing:.08em}\n.scn-pe .pe-num{color:var(--muted)}\n.scn-pe .pe-dose{background:var(--pink);color:#fff;border-radius:999px;padding:4px 12px}\n.scn-pe .pe-ing h3 span{display:block;font-size:16px;font-weight:600;color:var(--muted);margin-top:4px}\n.scn-pe details{border:1px solid var(--line);border-radius:12px;margin:0 0 10px;background:#fff}\n.scn-pe summary{cursor:pointer;padding:16px 48px 16px 18px;font-weight:700;list-style:none;position:relative}\n.scn-pe summary::-webkit-details-marker{display:none}\n.scn-pe summary:after{content:\"+\";position:absolute;right:18px;top:12px;font-size:22px;color:var(--pink);font-weight:800}\n.scn-pe details[open] summary:after{content:\"\u2013\"}\n.scn-pe details>div{padding:0 18px 14px}\n.scn-pe .pe-warn{background:#fafafb;border:1px solid var(--line);border-radius:14px;padding:22px;margin:16px 0}\n@media (max-width:600px){.scn-pe .pe-hero{padding:28px 18px}.scn-pe .pe-ing,.scn-pe .pe-aud{padding:20px 16px}}\n<\/style>\n<div class=\"scn-pe\">\n<div class=\"pe-hero\">\n<span class=\"pe-eyebrow\">SCN\u2122 Sport Line \u00b7 Energy | VO2 Max<\/span><\/p>\n<h2>The Endurance Pre-Workout That Keeps Working for Up to 4 Hours<\/h2>\n<p>Most pre-workouts are built for a 45-minute gym session: a fast caffeine spike, a big pump, then a crash just as an endurance athlete is settling into the real work. Pre-Endurance Training Activator is an <strong>endurance pre-workout<\/strong> built the other way round. SCN\u2122 developed it after eight years of analysing the training needs of the top athletes we work with, for long, high-intensity sessions and race days of two to four hours.<\/p>\n<p>Each peach-flavoured sachet delivers a complete nitric oxide and nitrate stack, <strong>6,000 mg L-citrulline DL-malate, 3,000 mg arginine alpha-ketoglutarate and 2,000 mg arginine nitrate<\/strong>, with 600 mg grape seed extract, L-tyrosine, glucuronolactone, SenActiv\u00ae, ZincNova\u2122 zinc, vitamin C, vitamins B1, B2 and niacin, and BioPerine\u00ae. The caffeine comes separately: two <strong>NewCaff\u2122 microencapsulated capsules<\/strong> that release 450 mg of caffeine gradually over up to four hours. Take them with the sachet or leave them out. Your session decides.<\/p>\n<ul class=\"pe-stats\">\n<li><b>13<\/b>active ingredients in every sachet<\/li>\n<li><b>6,000 mg<\/b>L-citrulline DL-malate 2:1<\/li>\n<li><b>2,000 mg<\/b>arginine nitrate<\/li>\n<li><b>4 h<\/b>NewCaff\u2122 slow caffeine release<\/li>\n<li><b>10<\/b>full servings per box<\/li>\n<\/ul>\n<\/div>\n<div class=\"pe-banner\">Long Endurance in High-Intensity Training<small>Our promise to you: train longer and harder\u2026 for sure.<\/small><\/div>\n<div class=\"pe-grid3\">\n<div class=\"pe-card\">\n<h3>Flow<\/h3>\n<p>Citrulline malate, arginine AKG, arginine nitrate and grape seed extract raise nitric oxide through two separate pathways, for more blood flow and more oxygen to working muscle, from the first kilometre to the last.<\/p>\n<\/div>\n<div class=\"pe-card\">\n<h3>Drive<\/h3>\n<p>L-tyrosine and glucuronolactone keep you sharp and push back fatigue, while vitamins B1, B2 and niacin contribute to normal energy-yielding metabolism and to the reduction of tiredness and fatigue.<\/p>\n<\/div>\n<div class=\"pe-card\">\n<h3>Last<\/h3>\n<p>NewCaff\u2122 releases caffeine steadily for up to four hours with no spike and no crash, and SenActiv\u00ae supports recovery so the next session starts fresh.<\/p>\n<\/div>\n<\/div>\n<h2>What This Endurance Pre-Workout Does<\/h2>\n<div class=\"pe-two\">\n<div>\n<ul>\n<li>Improves <strong>blood flow<\/strong> to working muscles<\/li>\n<li>Improves <strong>oxygen and nutrient supply<\/strong> to cells<\/li>\n<li>Increases <strong>VO2 max and endurance<\/strong> in long, hard sessions<\/li>\n<li>Increases <strong>performance and training intensity<\/strong><\/li>\n<li>Increases <strong>peak power output and explosive strength<\/strong><\/li>\n<\/ul>\n<\/div>\n<div>\n<ul>\n<li>Delays <strong>lactic acid<\/strong> build-up<\/li>\n<li>Improves <strong>heart rate recovery<\/strong> time<\/li>\n<li>Increases the <strong>fat and glucose metabolic rate<\/strong><\/li>\n<li>High <strong>thermogenic<\/strong> effect<\/li>\n<li>Improves <strong>recovery<\/strong> time<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2>An Endurance Pre-Workout With or Without Caffeine<\/h2>\n<p>The sachet itself is stimulant-free. The caffeine is packed separately in NewCaff\u2122 blisters, so you choose session by session instead of being locked into one formula. Buy Pre-Endurance with the capsules and use them only when the session calls for it.<\/p>\n<div class=\"pe-grid3\">\n<div class=\"pe-card\">\n<h3>Long and race-pace sessions<\/h3>\n<p><strong>1 sachet + 2 NewCaff\u2122 capsules.<\/strong> The full formula for key workouts, long rides and runs, and race day.<\/p>\n<\/div>\n<div class=\"pe-card\">\n<h3>Evening or stimulant-free sessions<\/h3>\n<p><strong>1 sachet on its own.<\/strong> Nitric oxide, nitrate, focus and vitamins without any stimulants, for late sessions or if you are sensitive to caffeine.<\/p>\n<\/div>\n<div class=\"pe-card\">\n<h3>Athletes under 65 kg<\/h3>\n<p><strong>\u00bd sachet + 1 NewCaff\u2122 capsule.<\/strong> Lighter athletes get the full benefit of the formula from half the dose.<\/p>\n<\/div>\n<\/div>\n<p><strong>Why slow-release caffeine?<\/strong> Ordinary caffeine, anhydrous or HCl, is absorbed within minutes and peaks in the blood after about an hour. For a long session that means trembling hands and an overstimulated start, then a sudden drop in energy and a struggle to keep going after 40 to 45 minutes. NewCaff\u2122 is caffeine enclosed in liposomal microcapsules that release it gradually over up to four hours, so you get the proven endurance benefits of caffeine in small, even amounts across the whole session. That is how this endurance pre-workout helps you complete a two to three hour session with stable energy and 10 to 15% more intensity.<\/p>\n<div class=\"pe-banner\">Train Longer and Harder\u2026 For Sure<small>The ultimate nitric oxide and nitrate formula for long, high-intensity endurance training.<\/small><\/div>\n<h2>The Endurance Pre-Workout for Runners, Cyclists, Triathletes and Every Long Session<\/h2>\n<p>One formula, built for the sports where the hard part starts after an hour. Here is what Pre-Endurance Training Activator does for you.<\/p>\n<div class=\"pe-aud\">\n<span class=\"pe-tag\">For Runners and Marathon Runners<\/span><\/p>\n<h3>Hold Your Pace When the Long Run Gets Hard<\/h3>\n<p><strong>The last third of a long run is where races are won and lost.<\/strong> Arginine nitrate lowers the oxygen cost of running at a given pace, so the same speed feels easier for longer. Citrulline malate helps clear ammonia and reduces fatigue in prolonged exercise, and L-tyrosine supports focus when legs and mind both want to slow down. NewCaff\u2122 keeps caffeine working through the full distance instead of fading at the halfway mark.<\/p>\n<p class=\"pe-howto\"><strong>How to use it:<\/strong> 1 sachet with 2 NewCaff\u2122 capsules 30 to 40 minutes before your warm-up. For runs over 2.5 hours, split the dose (see below).<\/p>\n<\/div>\n<div class=\"pe-aud\">\n<span class=\"pe-tag\">For Cyclists<\/span><\/p>\n<h3>More Watts for the Same Oxygen<\/h3>\n<p><strong>On the bike, efficiency is everything.<\/strong> Nitric oxide from two pathways widens blood vessels and improves oxygen and nutrient delivery to the legs, and the nitrate pathway keeps working when muscle is low on oxygen during climbs and hard intervals. Grape seed extract, studied together with citrulline in cycling tests, supports oxygen delivery to working muscle. Steady four-hour caffeine supports power and lowers perceived effort from the first climb to the final sprint.<\/p>\n<p class=\"pe-howto\"><strong>How to use it:<\/strong> 1 sachet with 2 NewCaff\u2122 capsules 30 to 40 minutes before you ride. On long rides over 150 minutes, take half before the start and half 60 minutes later.<\/p>\n<\/div>\n<div class=\"pe-aud\">\n<span class=\"pe-tag\">For Triathletes and Swimmers<\/span><\/p>\n<h3>Steady Energy Through Every Discipline<\/h3>\n<p><strong>Swim, bike and run ask for three different kinds of effort, and caffeine that peaks and crashes serves none of them.<\/strong> NewCaff\u2122 delivers caffeine evenly for up to four hours, long enough to cover a standard-distance race or a long brick session. Vitamin C contributes to the normal function of the immune system during and after intense physical exercise, and ZincNova\u2122 helps replace the zinc lost in sweat during heavy training blocks. Swimmers get the blood-flow and focus benefits without a stimulant spike before technical sets.<\/p>\n<p class=\"pe-howto\"><strong>How to use it:<\/strong> 1 sachet with 2 NewCaff\u2122 capsules 30 to 40 minutes before the swim warm-up. Test it in a training session before using it on race day.<\/p>\n<\/div>\n<div class=\"pe-aud\">\n<span class=\"pe-tag\">For High-Intensity, Hybrid and Team Sports<\/span><\/p>\n<h3>Power That Lasts Beyond the First 40 Minutes<\/h3>\n<p><strong>Hybrid racing, interval sessions and team sports demand power again and again.<\/strong> Citrulline malate and arginine nitrate support peak power output, muscle contraction efficiency and repeated efforts, while glucuronolactone and tyrosine support reaction time and concentration. Because the caffeine releases slowly, the second half of the session gets the same drive as the first.<\/p>\n<p class=\"pe-howto\"><strong>How to use it:<\/strong> 1 sachet with 2 NewCaff\u2122 capsules 30 to 40 minutes before your warm-up, or the sachet alone for evening sessions.<\/p>\n<\/div>\n<div class=\"pe-aud\">\n<span class=\"pe-tag\">For Active Ageing and Brain Health<\/span><\/p>\n<h3>Circulation, Focus and Cellular Renewal, Stimulant-Free<\/h3>\n<p><strong>Staying active for decades means looking after blood flow, the brain and recovery.<\/strong> Used without the NewCaff\u2122 capsules, the sachet is a stimulant-free formula for healthy circulation: citrulline and arginine support nitric oxide, vitamin C contributes to normal collagen formation for the normal function of blood vessels, and grape seed proanthocyanidins protect cells from oxidative damage. L-tyrosine supports focus and mental performance under stress, and SenActiv\u00ae supports the clearance of worn-out, ageing cells from muscle after exercise.<\/p>\n<p class=\"pe-howto\"><strong>How to use it:<\/strong> 1 sachet (or \u00bd sachet) without capsules, 30 to 40 minutes before your walk, ride, swim or gym session.<\/p>\n<\/div>\n<h2>How to Use Pre-Endurance Training Activator and What Is in Every Serving<\/h2>\n<div class=\"pe-steps\">\n<div><b>1 sachet (26.5 g)<\/b>mixed into 250 ml of room-temperature water<\/div>\n<div><b>30\u201340 minutes<\/b>before your warm-up, together with 2 NewCaff\u2122 capsules<\/div>\n<div><b>Over 150 minutes?<\/b>\u00bd sachet in 200 ml water + 1 capsule 40 minutes before the warm-up, then the same again 60 minutes after the first dose<\/div>\n<\/div>\n<p><strong>Tip for athletes under 65 kg:<\/strong> you can get all the benefits of the formula from half the recommended dose: \u00bd sachet with 1 NewCaff\u2122 capsule.<\/p>\n<div class=\"pe-table-wrap\">\n<table>\n<thead>\n<tr>\n<th>Ingredient<\/th>\n<th>Per 1 sachet (26.5 g)<\/th>\n<th>%NRV*<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>L-Citrulline DL-Malate 2:1<\/td>\n<td>6,000 mg<\/td>\n<td>\u2013<\/td>\n<\/tr>\n<tr>\n<td>L-Arginine Alpha-Ketoglutarate<\/td>\n<td>3,000 mg<\/td>\n<td>\u2013<\/td>\n<\/tr>\n<tr>\n<td>Arginine Nitrate<\/td>\n<td>2,000 mg<\/td>\n<td>\u2013<\/td>\n<\/tr>\n<tr>\n<td>L-Tyrosine<\/td>\n<td>1,500 mg<\/td>\n<td>\u2013<\/td>\n<\/tr>\n<tr>\n<td>Glucuronolactone<\/td>\n<td>1,400 mg<\/td>\n<td>\u2013<\/td>\n<\/tr>\n<tr>\n<td>Grape seed extract (<em>Vitis vinifera<\/em> L.)<\/td>\n<td>600 mg<\/td>\n<td>\u2013<\/td>\n<\/tr>\n<tr>\n<td class=\"pe-sub\">of which proanthocyanidins (95%)<\/td>\n<td>570 mg<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Vitamin C<\/td>\n<td>500 mg<\/td>\n<td>625%<\/td>\n<\/tr>\n<tr>\n<td>ZincNova\u2122 microencapsulated liposomal zinc<\/td>\n<td>125 mg<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td class=\"pe-sub\">providing elemental zinc<\/td>\n<td>25 mg<\/td>\n<td>250%<\/td>\n<\/tr>\n<tr>\n<td>Niacin<\/td>\n<td>120 mg NE<\/td>\n<td>750%<\/td>\n<\/tr>\n<tr>\n<td>SenActiv\u00ae (<em>Panax notoginseng<\/em> &amp; <em>Rosa canina<\/em> extracts)<\/td>\n<td>100 mg<\/td>\n<td>\u2013<\/td>\n<\/tr>\n<tr>\n<td>Vitamin B1 (thiamine)<\/td>\n<td>79 mg<\/td>\n<td>7182%<\/td>\n<\/tr>\n<tr>\n<td>Vitamin B2 (riboflavin)<\/td>\n<td>30 mg<\/td>\n<td>2143%<\/td>\n<\/tr>\n<tr>\n<td>BioPerine\u00ae black pepper extract (<em>Piper nigrum<\/em> L.)<\/td>\n<td>30 mg<\/td>\n<td>\u2013<\/td>\n<\/tr>\n<tr>\n<td class=\"pe-sub\">of which piperine (95%)<\/td>\n<td>28.5 mg<\/td>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"pe-table-wrap\">\n<table>\n<thead>\n<tr>\n<th>Pre-Endurance slow-release caffeine<\/th>\n<th>Per serving (2 capsules)<\/th>\n<th>%NRV*<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>NewCaff\u2122 micro-liposomal slow-release caffeine<\/td>\n<td>600 mg<\/td>\n<td>\u2013<\/td>\n<\/tr>\n<tr>\n<td class=\"pe-sub\">providing caffeine<\/td>\n<td>450 mg<\/td>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p class=\"pe-caption\">*NRV: Nutrient Reference Value. \u2013 = no NRV established.<\/p>\n<p><strong>Product info:<\/strong> Powder: 10 sachets of 26.5 g, peach flavour, 10 full or 20 half servings. NewCaff\u2122 capsules: 2 blisters of 10 capsules (20 capsules, 10 full servings), available in packs of 20, 40, 80 or 120 capsules, or choose the powder without capsules. The sachet format keeps every serving fresh and stable for longer.<\/p>\n<h2>Inside the Formula: 14 Ingredients, Each With a Job<\/h2>\n<p>Nothing in this endurance pre-workout is there to fill the label. Our best-selling formula was upgraded with 60% more L-tyrosine and glucuronolactone and five new ingredients, including arginine nitrate, a high dose of grape seed proanthocyanidins and SenActiv\u00ae. Here is every ingredient in full: what it is, what the research says, why it is in the formula and what it does for your health and your sport.<\/p>\n<div class=\"pe-jump\">\n<a href=\"#pe-citrulline\">L-Citrulline DL-Malate<\/a><a href=\"#pe-aakg\">Arginine AKG<\/a><a href=\"#pe-nitrate\">Arginine Nitrate<\/a><a href=\"#pe-tyrosine\">L-Tyrosine<\/a><a href=\"#pe-glucuro\">Glucuronolactone<\/a><a href=\"#pe-grape\">Grape Seed Extract<\/a><a href=\"#pe-vitc\">Vitamin C<\/a><a href=\"#pe-zinc\">ZincNova\u2122 Zinc<\/a><a href=\"#pe-niacin\">Niacin<\/a><a href=\"#pe-senactiv\">SenActiv\u00ae<\/a><a href=\"#pe-b1\">Vitamin B1<\/a><a href=\"#pe-b2\">Vitamin B2<\/a><a href=\"#pe-bioperine\">BioPerine\u00ae<\/a><a href=\"#pe-newcaff\">NewCaff\u2122 Caffeine<\/a>\n<\/div>\n<section class=\"pe-ing\" id=\"pe-citrulline\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">01 \/ 14<\/span><span class=\"pe-dose\">6,000 mg per sachet<\/span><\/div>\n<h3>L-Citrulline DL-Malate 2:1 <span>The Nitric Oxide Engine of the Formula<\/span><\/h3>\n<h4>What is L-citrulline DL-malate?<\/h4>\n<p>L-citrulline is an amino acid first identified in watermelon (<em>Citrullus lanatus<\/em>), which gave it its name. In citrulline malate 2:1, two parts of L-citrulline are bound to one part of DL-malic acid, so the 6,000 mg in each sachet supplies about 4,000 mg of citrulline and 2,000 mg of malate. It is the highest dose in the formula.<\/p>\n<h4>The science of citrulline malate<\/h4>\n<p>Citrulline is one of the three amino acids of the urea cycle, alongside L-arginine and L-ornithine. Unlike arginine, it is not broken down in the gut and liver: it travels to the kidneys, which convert it into arginine. That is why supplemented citrulline raises blood arginine more effectively than arginine itself, keeping the enzymes that make nitric oxide supplied for longer. Citrulline also raises ornithine levels and improves the recycling of ammonia, a by-product of hard exercise that is linked with fatigue.<\/p>\n<p>Malate is an intermediate of the Krebs cycle, the main energy pathway in your cells, and has its own ergogenic effect. In research, citrulline supplementation reduced fatigue and improved endurance in prolonged aerobic and anaerobic exercise, and in a well-known study, 8 g of citrulline malate before training increased the number of repetitions performed and reduced muscle soreness over the following days.<\/p>\n<h4>Formula synergy: citrulline malate in Pre-Endurance<\/h4>\n<p>Citrulline is the slow, steady supply line for nitric oxide. Arginine AKG feeds the same pathway straight away, arginine nitrate adds a second pathway that works when oxygen runs low, and grape seed extract was studied specifically in combination with citrulline for oxygen delivery to working muscle.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>Citrulline malate health benefits<\/h5>\n<ul>\n<li>Supports nitric oxide production and healthy blood flow<\/li>\n<li>Supports healthy circulation and heart function<\/li>\n<li>Supports the clearance of ammonia<\/li>\n<li>Supports cellular energy production through malate<\/li>\n<li>Raises blood arginine more effectively than arginine itself<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>Citrulline malate sport benefits<\/h5>\n<ul>\n<li>More endurance, more oxygen and less lactic acid<\/li>\n<li>Reduces fatigue in prolonged aerobic and anaerobic exercise<\/li>\n<li>Increases peak power output<\/li>\n<li>Gives endurance at high intensity, so you train harder and longer<\/li>\n<li>Reduces muscle soreness after training<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-aakg\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">02 \/ 14<\/span><span class=\"pe-dose\">3,000 mg per sachet<\/span><\/div>\n<h3>L-Arginine Alpha-Ketoglutarate <span>Direct Fuel for Nitric Oxide and Cellular Energy<\/span><\/h3>\n<h4>What is arginine AKG?<\/h4>\n<p>Arginine alpha-ketoglutarate (AAKG) combines the amino acid L-arginine with alpha-ketoglutarate (AKG), a keto acid derived from glutaric acid. Arginine is the amino acid your body uses to make nitric oxide directly; AKG is one of the key molecules of cellular energy metabolism.<\/p>\n<h4>The science of arginine AKG<\/h4>\n<p>Nitric oxide synthase enzymes convert L-arginine directly into nitric oxide, the signal that relaxes and widens blood vessels. The citrulline released in this reaction can be recycled back into arginine, which is why arginine and citrulline work as a loop rather than two separate ingredients.<\/p>\n<p>AKG takes part in several reactions of the Krebs cycle, the main mechanism of energy production in your cells, and is one of the most important nitrogen carriers in metabolic pathways. It helps break down sugars and amino acids, including arginine and citrulline, which makes the two core ingredients of the formula even more effective. AKG also increases the metabolic rate of L-proline and hydroxyproline, which play a key role in the formation of type I collagen, the collagen of tendons, ligaments and bone.<\/p>\n<h4>Formula synergy: arginine AKG in Pre-Endurance<\/h4>\n<p>Arginine AKG supplies nitric oxide production immediately, while citrulline malate keeps it going for hours. Combined, arginine AKG and citrulline malate help athletes bring their heart rate down faster during and after training.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>Arginine AKG health benefits<\/h5>\n<ul>\n<li>Supports nitric oxide production and blood vessel function<\/li>\n<li>Supports energy production in the Krebs cycle<\/li>\n<li>Supports the formation of type I collagen<\/li>\n<li>Supports nitrogen transport in metabolism<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>Arginine AKG sport benefits<\/h5>\n<ul>\n<li>Improves blood flow and oxygen delivery to working muscle<\/li>\n<li>Helps you increase performance and train longer<\/li>\n<li>Supports faster heart rate recovery during and after training<\/li>\n<li>Supports the use of sugars and amino acids for energy<\/li>\n<li>Supports tendons and connective tissue under training load<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-nitrate\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">03 \/ 14<\/span><span class=\"pe-dose\">2,000 mg per sachet<\/span><\/div>\n<h3>Arginine Nitrate <span>The Nitrate Pathway That Works When Oxygen Runs Low<\/span><\/h3>\n<h4>What is arginine nitrate?<\/h4>\n<p>Arginine nitrate is L-arginine bonded to nitrate, the same compound that made beetroot juice famous among endurance athletes. About a quarter of its weight is nitrate, so each sachet provides roughly 500 mg of nitrate, in the range used in many endurance studies, alongside a further dose of arginine.<\/p>\n<h4>The science of arginine nitrate<\/h4>\n<p>Nitrate reaches nitric oxide by a completely different route from arginine and citrulline. Bacteria on your tongue convert nitrate into nitrite, which the body then turns into nitric oxide, and this conversion works best in exactly the low-oxygen, acidic conditions found in hard-working muscle, when the arginine pathway slows down. In controlled studies, dietary nitrate lowered the oxygen cost of submaximal exercise: the same workload required less oxygen. Research also shows nitrates enhance the efficiency of muscle contraction, which supports both endurance and strength.<\/p>\n<p>Arginine nitrate improves blood flow not only during training but for hours afterwards. Wider blood vessels carry oxygen and nutrients to muscle, help remove lactic acid during the session and, after it, push your recovery nutrition, such as a protein shake, into the muscles to kick-start repair. It also raises energy levels without any additional stimulants.<\/p>\n<h4>Formula synergy: arginine nitrate in Pre-Endurance<\/h4>\n<p>Two pathways to nitric oxide mean blood flow support across the whole session, from the easy warm-up to the oxygen-starved final effort. Vitamin C and grape seed proanthocyanidins help protect the nitric oxide produced from oxidation.<\/p>\n<p><strong>Tip:<\/strong> antibacterial mouthwash kills the tongue bacteria that convert nitrate, so avoid it in the hours around your serving.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>Arginine nitrate health benefits<\/h5>\n<ul>\n<li>Boosts nitric oxide production<\/li>\n<li>Improves blood flow, during and for hours after exercise<\/li>\n<li>Supports the delivery of oxygen and nutrients to cells<\/li>\n<li>Raises energy levels without stimulants<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>Arginine nitrate sport benefits<\/h5>\n<ul>\n<li>Increases endurance and stamina<\/li>\n<li>Lowers the oxygen cost of exercise<\/li>\n<li>Boosts strength and power through more efficient muscle contraction<\/li>\n<li>Helps remove lactic acid build-up during training<\/li>\n<li>Enhances recovery by delivering nutrients to muscle after training<\/li>\n<li>Works in stimulant-free sessions as well as with caffeine<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-tyrosine\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">04 \/ 14<\/span><span class=\"pe-dose\">1,500 mg per sachet<\/span><\/div>\n<h3>L-Tyrosine <span>Focus and Drive When Fatigue Sets In<\/span><\/h3>\n<h4>What is L-tyrosine?<\/h4>\n<p>L-tyrosine is an amino acid the body uses to make dopamine and noradrenaline, the brain messengers behind motivation, alertness and focus, as well as adrenaline and thyroid hormones. The upgraded formula contains 60% more tyrosine than the original.<\/p>\n<h4>The science of L-tyrosine<\/h4>\n<p>Under stress and during long, hard exercise, the brain uses up its dopamine and noradrenaline faster than it can replace them, which is one of the causes of central fatigue: the feeling that your head wants to stop before your legs do. Supplemental tyrosine helps keep these messengers available. In studies, tyrosine supported attention, working memory and mental performance under demanding conditions such as cold, sleep loss and multitasking. Many people also notice a sense of well-being and a slight lift in mood.<\/p>\n<h4>Formula synergy: L-tyrosine in Pre-Endurance<\/h4>\n<p>Tyrosine works on the brain side of fatigue, alongside caffeine and glucuronolactone. Vitamins B1, B2 and niacin contribute to the normal function of the nervous system, and BioPerine\u00ae helps it absorb.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>L-tyrosine health benefits<\/h5>\n<ul>\n<li>Increases attention and focus<\/li>\n<li>Supports mental performance under stress<\/li>\n<li>Helps decrease stress levels<\/li>\n<li>Gives a sense of well-being and supports a balanced mood<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>L-tyrosine sport benefits<\/h5>\n<ul>\n<li>Fights fatigue in endurance performance<\/li>\n<li>Reduces reaction time<\/li>\n<li>Helps improve the intensity of your workout<\/li>\n<li>Supports the recovery of the central nervous system after training<\/li>\n<li>Keeps you mentally sharp in the late stages of a race<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-glucuro\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">05 \/ 14<\/span><span class=\"pe-dose\">1,400 mg per sachet<\/span><\/div>\n<h3>Glucuronolactone <span>For Physical and Mental Performance<\/span><\/h3>\n<h4>What is glucuronolactone?<\/h4>\n<p>Glucuronolactone (D-glucurono-gamma-lactone) is a naturally occurring white compound that your body makes from glucose. It is present only in small amounts in the diet and is best known as an ingredient in energy drinks. In the body it exists in balance with glucuronic acid, so supplementing glucuronolactone boosts glucuronic acid and the related phase II process of glucuronidation, one of the liver&#8217;s natural ways of processing and clearing substances.<\/p>\n<h4>The science of glucuronolactone<\/h4>\n<p>In physiological trials, glucuronolactone inhibited the formation of toxic by-products of intensive exercise and other causes of fatigue (Tamura et al., 1968). When people were given an energy drink combining glucuronolactone, caffeine and taurine, they showed improvements in aerobic and anaerobic performance, and in reaction time, concentration and memory, compared with a control (Alford et al., 2001). In pre-workout supplements combining these ingredients, glucuronolactone was associated with more total repetitions and a greater anabolic response (Hoffman et al., 2008), results later reproduced by the same research group (Gonzalez et al., 2011). Typical doses in supplements and energy drinks are generally considered safe.<\/p>\n<h4>Formula synergy: glucuronolactone in Pre-Endurance<\/h4>\n<p>Glucuronolactone has an excellent synergistic effect with citrulline and caffeine, which is exactly how it is combined in this formula. The upgraded formula contains 60% more of it than the original.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>Glucuronolactone health benefits<\/h5>\n<ul>\n<li>Supports mental performance: reaction time, concentration and memory<\/li>\n<li>Supports the body&#8217;s glucuronidation pathway<\/li>\n<li>May support liver function<\/li>\n<li>A natural human metabolite made from glucose<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>Glucuronolactone sport benefits<\/h5>\n<ul>\n<li>Helps inhibit fatigue-causing by-products of intense exercise<\/li>\n<li>Supports aerobic and anaerobic performance<\/li>\n<li>Associated with more repetitions in strength training<\/li>\n<li>May help increase strength and lean gains with weight training<\/li>\n<li>Keeps you focused through long sessions<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-grape\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">06 \/ 14<\/span><span class=\"pe-dose\">600 mg (570 mg proanthocyanidins)<\/span><\/div>\n<h3>Grape Seed Extract 95% Proanthocyanidins <span>The Oxygen Delivery Partner for Citrulline<\/span><\/h3>\n<h4>What is grape seed extract?<\/h4>\n<p>Grape seed extract comes from the seeds of the wine grape, <em>Vitis vinifera<\/em>. The extract in this formula is standardised to 95% proanthocyanidins (OPCs), powerful polyphenol antioxidants, giving a massive 570 mg of proanthocyanidins in every sachet: a training effect you can feel from the very first dose.<\/p>\n<h4>The science of grape seed extract<\/h4>\n<p>Proanthocyanidins support the blood vessel lining&#8217;s own production of nitric oxide and help protect nitric oxide from being broken down by oxidation. Studies on the blood-flow effects of grape seed extract date back to the late 1990s, and researchers at California Baptist University, publishing in the <em>Journal of Dietary Supplements<\/em>, set out to test whether it improves oxygen delivery to working muscle, and whether it adds to the effect of L-citrulline.<\/p>\n<p>Their four-arm, double-blind, placebo-controlled crossover study recruited 11 healthy young men, who each took a placebo, 6 g of L-citrulline, L-citrulline with 600 mg of grape seed extract, and grape seed extract alone, for one week each with a washout week in between. On a cycling ergometer at 30%, 60% and 80% of their maximum, the researchers measured blood pressure, oxygen consumption (VO2), stroke volume and cardiac output, and reported significant improvements in oxygen cost to exhaustion and in time-trial performance.<\/p>\n<h4>Formula synergy: grape seed extract in Pre-Endurance<\/h4>\n<p>Pre-Endurance uses the same 600 mg dose of grape seed extract as the study, paired with citrulline. Vitamin C works alongside it as an antioxidant and contributes to normal collagen formation for the normal function of blood vessels.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>Grape seed extract health benefits<\/h5>\n<ul>\n<li>Improves blood flow and supports healthy circulation<\/li>\n<li>Reduces oxidative damage<\/li>\n<li>Supports brain health and memory<\/li>\n<li>Supports collagen levels and bone strength<\/li>\n<li>Supports wound healing<\/li>\n<li>Supports liver health<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>Grape seed extract sport benefits<\/h5>\n<ul>\n<li>Speeds oxygen delivery to working muscles<\/li>\n<li>Supports vasodilation together with citrulline<\/li>\n<li>Associated with a lower oxygen cost and better time-trial performance<\/li>\n<li>Antioxidant protection through long sessions<\/li>\n<li>Helps reduce swelling after knocks and strains<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-vitc\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">07 \/ 14<\/span><span class=\"pe-dose\">500 mg \u00b7 625% NRV<\/span><\/div>\n<h3>Vitamin C <span>Immune and Blood Vessel Support Under Training Load<\/span><\/h3>\n<h4>What is vitamin C?<\/h4>\n<p>Vitamin C (ascorbic acid) is a water-soluble vitamin and one of the body&#8217;s main antioxidants. Humans cannot make it, so it must come from food or supplements. Each sachet provides 500 mg, 625% of the Nutrient Reference Value.<\/p>\n<h4>The science of vitamin C<\/h4>\n<p>Vitamin C is needed to build collagen, including the collagen in the walls of your blood vessels, and it helps preserve nitric oxide by protecting it from oxidation. Hard endurance training temporarily increases oxidative stress and puts pressure on the immune system, which is why vitamin C has a recognised role in the normal function of the immune system during and after intense physical exercise when taken at 200 mg or more on top of a normal diet.<\/p>\n<h4>Formula synergy: vitamin C in Pre-Endurance<\/h4>\n<p>Vitamin C supports the blood vessels that the nitric oxide stack opens up, and adds to the antioxidant protection of grape seed proanthocyanidins.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>Vitamin C health benefits<\/h5>\n<ul>\n<li>Contributes to normal collagen formation for the normal function of blood vessels<\/li>\n<li>Contributes to the normal function of the immune system<\/li>\n<li>Contributes to the protection of cells from oxidative stress<\/li>\n<li>Contributes to normal psychological function<\/li>\n<li>Increases iron absorption<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>Vitamin C sport benefits<\/h5>\n<ul>\n<li>Contributes to maintaining the normal function of the immune system during and after intense physical exercise<\/li>\n<li>Contributes to the reduction of tiredness and fatigue<\/li>\n<li>Contributes to normal energy-yielding metabolism<\/li>\n<li>Contributes to normal collagen formation for the normal function of bones and cartilage<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-zinc\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">08 \/ 14<\/span><span class=\"pe-dose\">125 mg (25 mg zinc) \u00b7 250% NRV<\/span><\/div>\n<h3>ZincNova\u2122 Microencapsulated Liposomal Zinc <span>The Mineral Endurance Athletes Sweat Out<\/span><\/h3>\n<h4>What is ZincNova\u2122?<\/h4>\n<p>ZincNova\u2122 is a non-reactive form of zinc oxide microencapsulated in a food-grade fat carrier. The coating stops the zinc from taking up moisture and from reacting with the other ingredients in the formula, which preserves its bioavailability, and it keeps zinc&#8217;s metallic taste out of your drink. The 125 mg in each sachet supplies 25 mg of elemental zinc, 250% of the Nutrient Reference Value.<\/p>\n<h4>The science of zinc<\/h4>\n<p>Zinc is the most widespread trace element in the body and takes part in hundreds of enzymes in major biochemical pathways. It is lost in sweat, so athletes who train for hours are at higher risk of running low. In trained male athletes, zinc supplementation increased muscle strength and endurance. Low zinc levels are linked with lower testosterone, which affects strength, body composition and recovery, and zinc is involved in building and repairing muscle.<\/p>\n<h4>Formula synergy: zinc in Pre-Endurance<\/h4>\n<p>Zinc and vitamin C together support the immune system through hard training blocks, while zinc&#8217;s role in protein synthesis supports the recovery side of the formula.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>Zinc health benefits<\/h5>\n<ul>\n<li>Contributes to the normal function of the immune system<\/li>\n<li>Contributes to the maintenance of normal testosterone levels in the blood<\/li>\n<li>Contributes to normal cognitive function<\/li>\n<li>Contributes to the protection of cells from oxidative stress<\/li>\n<li>Contributes to the maintenance of normal bones, skin, hair and nails<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>Zinc sport benefits<\/h5>\n<ul>\n<li>Helps replace the zinc lost in sweat<\/li>\n<li>Contributes to normal protein synthesis<\/li>\n<li>Contributes to normal macronutrient and carbohydrate metabolism<\/li>\n<li>Contributes to normal acid-base metabolism<\/li>\n<li>Supports strength, endurance and wound healing in athletes<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-niacin\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">09 \/ 14<\/span><span class=\"pe-dose\">120 mg NE \u00b7 750% NRV<\/span><\/div>\n<h3>Niacin (Vitamin B3) <span>The Vitamin Behind NAD and Cellular Energy<\/span><\/h3>\n<h4>What is niacin?<\/h4>\n<p>Niacin is vitamin B3, measured in niacin equivalents (NE). Each sachet provides 120 mg NE, 750% of the Nutrient Reference Value.<\/p>\n<h4>The science of niacin<\/h4>\n<p>Your body uses niacin to make NAD and NADP, coenzymes that take part in hundreds of reactions. NAD carries the electrons released when carbohydrate and fat are broken down to the mitochondria, where they are turned into ATP, the energy that powers every muscle contraction. NAD levels fall with age, which has made it a focus of longevity research.<\/p>\n<h4>Formula synergy: niacin in Pre-Endurance<\/h4>\n<p>Niacin, vitamin B1 and vitamin B2 together cover the main steps of turning fuel into energy, so the extra oxygen delivered by the nitric oxide stack has the cofactors it needs.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>Niacin health benefits<\/h5>\n<ul>\n<li>Contributes to normal energy-yielding metabolism<\/li>\n<li>Contributes to the normal function of the nervous system<\/li>\n<li>Contributes to normal psychological function<\/li>\n<li>Contributes to the maintenance of normal skin and mucous membranes<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>Niacin sport benefits<\/h5>\n<ul>\n<li>Contributes to the reduction of tiredness and fatigue<\/li>\n<li>Supports energy release from carbohydrate and fat<\/li>\n<li>Supports mitochondrial energy production during long sessions<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-senactiv\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">10 \/ 14<\/span><span class=\"pe-dose\">100 mg per sachet<\/span><\/div>\n<h3>SenActiv\u00ae <span>Clearing Worn-Out Cells for Faster Recovery<\/span><\/h3>\n<h4>What is SenActiv\u00ae?<\/h4>\n<p>SenActiv\u00ae is a patented botanical ingredient combining extracts of <em>Panax notoginseng<\/em> root and rose fruit. It is one of the newest ingredients in performance nutrition, here to bring a new era in endurance and performance sports nutrition.<\/p>\n<h4>The science of SenActiv\u00ae<\/h4>\n<p>Intense training and ageing both leave behind senescent cells: damaged cells that have stopped dividing but do not die, and that release signals which slow down repair. SenActiv\u00ae is described as a senolytic ingredient, one that helps the body clear these worn-out cells. In human exercise studies funded by its developer, SenActiv\u00ae helped remove senescent cells from muscle after intense exercise, supported their replacement with new cells, and supported recovery and the replenishment of muscle glycogen.<\/p>\n<h4>Formula synergy: SenActiv\u00ae in Pre-Endurance<\/h4>\n<p>Most of this endurance pre-workout works during the session. SenActiv\u00ae works on what comes after it, so that today&#8217;s hard workout leads into a good one tomorrow.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>SenActiv\u00ae health benefits<\/h5>\n<ul>\n<li>Supports the clearance of senescent, worn-out cells<\/li>\n<li>Supports cellular renewal<\/li>\n<li>Anti-ageing and cell-protecting properties<\/li>\n<li>Supports a healthy inflammatory response<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>SenActiv\u00ae sport benefits<\/h5>\n<ul>\n<li>Supports faster recovery between sessions<\/li>\n<li>Supports muscle regeneration after intense exercise<\/li>\n<li>Supports muscle glycogen replenishment<\/li>\n<li>Helps maintain training quality through heavy blocks<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-b1\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">11 \/ 14<\/span><span class=\"pe-dose\">79 mg \u00b7 7182% NRV<\/span><\/div>\n<h3>Vitamin B1 (Thiamine) <span>The Gateway From Carbohydrate to Energy<\/span><\/h3>\n<h4>What is vitamin B1?<\/h4>\n<p>Thiamine is vitamin B1, a water-soluble vitamin the body stores only in small amounts. Each sachet provides 79 mg, 7182% of the Nutrient Reference Value.<\/p>\n<h4>The science of vitamin B1<\/h4>\n<p>In its active form, thiamine is the cofactor for the enzyme that moves the products of carbohydrate breakdown into the Krebs cycle. Without it, carbohydrate cannot be fully turned into energy, which makes it especially important for endurance athletes who burn large amounts of carbohydrate in long, hard sessions and race on carbohydrate drinks and gels.<\/p>\n<h4>Formula synergy: vitamin B1 in Pre-Endurance<\/h4>\n<p>Vitamin B1 links your carbohydrate fuel to energy production, while malate and AKG supply the Krebs cycle directly.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>Vitamin B1 health benefits<\/h5>\n<ul>\n<li>Contributes to normal energy-yielding metabolism<\/li>\n<li>Contributes to the normal function of the heart<\/li>\n<li>Contributes to the normal function of the nervous system<\/li>\n<li>Contributes to normal psychological function<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>Vitamin B1 sport benefits<\/h5>\n<ul>\n<li>Supports the use of carbohydrate as fuel<\/li>\n<li>Supports energy production in long sessions<\/li>\n<li>Supports the nervous system under training stress<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-b2\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">12 \/ 14<\/span><span class=\"pe-dose\">30 mg \u00b7 2143% NRV<\/span><\/div>\n<h3>Vitamin B2 (Riboflavin) <span>Energy, Red Blood Cells and Antioxidant Defence<\/span><\/h3>\n<h4>What is vitamin B2?<\/h4>\n<p>Riboflavin is vitamin B2, the vitamin that gives B-complex products their bright yellow colour. Each sachet provides 30 mg, 2143% of the Nutrient Reference Value.<\/p>\n<h4>The science of vitamin B2<\/h4>\n<p>Riboflavin forms FAD and FMN, coenzymes at the heart of the mitochondrial electron transport chain and of fat burning. It also keeps the antioxidant glutathione in its active form and takes part in iron metabolism, both important for athletes who train for hours.<\/p>\n<h4>Formula synergy: vitamin B2 in Pre-Endurance<\/h4>\n<p>Riboflavin completes the B-vitamin trio with niacin and thiamine, and supports the antioxidant work of vitamin C and grape seed extract.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>Vitamin B2 health benefits<\/h5>\n<ul>\n<li>Contributes to the protection of cells from oxidative stress<\/li>\n<li>Contributes to normal iron metabolism<\/li>\n<li>Contributes to the maintenance of normal red blood cells<\/li>\n<li>Contributes to the maintenance of normal vision and skin<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>Vitamin B2 sport benefits<\/h5>\n<ul>\n<li>Contributes to normal energy-yielding metabolism<\/li>\n<li>Contributes to the reduction of tiredness and fatigue<\/li>\n<li>Supports fat oxidation in long sessions<\/li>\n<li>Contributes to the normal function of the nervous system<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-bioperine\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">13 \/ 14<\/span><span class=\"pe-dose\">30 mg (28.5 mg piperine)<\/span><\/div>\n<h3>BioPerine\u00ae <span>The Lipo-Gluco-Metabolic Activator That Makes Every Ingredient Count<\/span><\/h3>\n<h4>What is BioPerine\u00ae?<\/h4>\n<p>BioPerine\u00ae is a patented extract of black pepper (<em>Piper nigrum<\/em>) standardised to 95% piperine, clinically studied for its safety and efficacy as a natural bioavailability enhancer and thermonutrient.<\/p>\n<h4>The science of BioPerine\u00ae<\/h4>\n<p>Piperine slows down some of the processes the gut and liver use to break down nutrients before they reach the bloodstream, so more of what you take is absorbed and stays active for longer. Of the many BioPerine\u00ae benefits, this &#8220;bioenhancement&#8221; is the best known: in a classic study, piperine increased the absorption of curcumin many times over, and it may do the same for nutrients such as vitamin C and the B vitamins. Piperine also supports thermogenesis, the heat your body produces, which increases metabolic rate, and in experimental research it supported dopamine and serotonin levels, memory and attention.<\/p>\n<h4>Formula synergy: BioPerine\u00ae in Pre-Endurance<\/h4>\n<p>BioPerine\u00ae is the absorption and action accelerator of the formula. It activates your metabolism for a bigger energy output and helps every other ingredient work better, so you get more from each sachet.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>BioPerine\u00ae health benefits<\/h5>\n<ul>\n<li>Increases the absorption of nutrients<\/li>\n<li>Supports metabolism through thermogenesis<\/li>\n<li>May support mood, memory and attention<\/li>\n<li>May support motivation and the management of stress<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>BioPerine\u00ae sport benefits<\/h5>\n<ul>\n<li>More from every ingredient in the formula<\/li>\n<li>Supports fat and glucose metabolism (lipo-gluco-metabolic effect)<\/li>\n<li>Supports a higher energy output<\/li>\n<li>Faster, more complete absorption before your session<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"pe-ing\" id=\"pe-newcaff\">\n<div class=\"pe-ing-head\"><span class=\"pe-num\">14 \/ 14<\/span><span class=\"pe-dose\">600 mg (450 mg caffeine) per 2 capsules<\/span><\/div>\n<h3>NewCaff\u2122 Slow-Release Caffeine <span>The 4-Hour Caffeine for Long Endurance Training and Races<\/span><\/h3>\n<h4>What is NewCaff\u2122?<\/h4>\n<p>NewCaff\u2122 is a patented sustained-release caffeine developed by Lipofoods, specialised for endurance sports and for anyone who dislikes the side effects of normal caffeine. Caffeine is enclosed in liposomal microcapsules that release it gradually, so its effects are felt for up to four hours. Two capsules provide 600 mg of NewCaff\u2122, which supplies 450 mg of caffeine. The capsules come in separate blisters, so you can use the formula with or without caffeine.<\/p>\n<h4>The science of caffeine<\/h4>\n<p>Caffeine may be the most widely used performance aid in the world, and for endurance athletes it is one of the best-researched. It works mainly on the brain, blocking adenosine, the signal that builds up as you tire, so the same effort feels easier. Research on well-trained athletes found that 3 to 9 mg of caffeine per kg of body weight, taken before exercise, increased running and cycling endurance. Caffeine may also help mobilise fat stores, sparing muscle glycogen early in exercise, and it helps recovery: four hours after exercise, muscle glycogen was 66% higher when athletes took caffeine with a carbohydrate drink than with carbohydrate alone.<\/p>\n<p>The problem is how ordinary caffeine is delivered. Caffeine anhydrous and caffeine HCl, used by most sports nutrition brands that do not specialise in endurance, are absorbed within minutes and peak about an hour later. A large dose arriving all at once brings trembling, overstimulation, digestive upset and a racing heart, followed by sudden exhaustion, which is why so many athletes struggle to keep training after 30 to 45 minutes. NewCaff\u2122 releases the same caffeine in small, even amounts over up to four hours, so you keep the benefits and avoid the spike and the crash.<\/p>\n<h4>Is caffeine allowed in competition?<\/h4>\n<p>Yes. Caffeine was removed from the World Anti-Doping Agency (WADA) Prohibited List in 2004 and is now only part of its monitoring programme. As with any supplement, use it responsibly and speak to your doctor if you have a medical condition or take medication.<\/p>\n<div class=\"pe-two\">\n<div>\n<h5>Caffeine health benefits<\/h5>\n<ul>\n<li>Increases alertness and attention<\/li>\n<li>Supports concentration and reaction time<\/li>\n<li>Steady energy for up to four hours with no crash<\/li>\n<li>Avoids the jitters and digestive upset of fast-acting caffeine<\/li>\n<\/ul>\n<\/div>\n<div>\n<h5>Caffeine sport benefits<\/h5>\n<ul>\n<li>Increases endurance performance<\/li>\n<li>Reduces perceived effort, so hard paces feel easier<\/li>\n<li>Supports fat use and glycogen sparing<\/li>\n<li>Supports glycogen refuelling with carbohydrate after training<\/li>\n<li>Keeps working through sessions of two to four hours<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n<div class=\"pe-banner\">Faster. Longer. Harder.<small>The most specialised endurance pre-workout for sessions of more than 2.5 hours.<\/small><\/div>\n<h2>Endurance Pre-Workout: Your Questions Answered<\/h2>\n<details>\n<summary>What is an endurance pre-workout?<\/summary>\n<div>\n<p>An endurance pre-workout is taken before training or racing to support blood flow, oxygen delivery, energy and focus over a long session, rather than for a short burst of stimulation. Pre-Endurance Training Activator combines a nitric oxide and nitrate stack (citrulline malate, arginine AKG, arginine nitrate and grape seed extract) with L-tyrosine, glucuronolactone, SenActiv\u00ae, vitamins and zinc, plus NewCaff\u2122 caffeine that releases over up to four hours.<\/p>\n<\/div>\n<\/details>\n<details>\n<summary>How is it different from a normal pre-workout?<\/summary>\n<div>\n<p>Most pre-workouts are designed for 45 to 60 minutes in the gym and use fast-acting caffeine that peaks and crashes. Pre-Endurance is built for sessions of two to four hours: the caffeine is slow-release and packed separately, the nitric oxide stack uses two pathways so it keeps working when muscle oxygen runs low, and the formula includes recovery and immune support for heavy training.<\/p>\n<\/div>\n<\/details>\n<details>\n<summary>When and how should I take it?<\/summary>\n<div>\n<p>Mix 1 sachet (26.5 g) into 250 ml of room-temperature water and drink it 30 to 40 minutes before your warm-up, together with 2 NewCaff\u2122 capsules. For sessions over 150 minutes, take \u00bd sachet in 200 ml of water with 1 capsule 40 minutes before the warm-up, and the same again 60 minutes after the first dose. Athletes under 65 kg can use \u00bd sachet with 1 capsule.<\/p>\n<\/div>\n<\/details>\n<details>\n<summary>How much caffeine is in each serving?<\/summary>\n<div>\n<p>Two NewCaff\u2122 capsules provide 450 mg of caffeine, released gradually over up to four hours. This is a strong dose designed for trained adult endurance athletes. If you are new to it, lighter than 65 kg or sensitive to caffeine, start with 1 capsule. Do not take more than 2 capsules a day, avoid other sources of caffeine on the same day, and avoid using the capsules late in the day.<\/p>\n<\/div>\n<\/details>\n<details>\n<summary>Can I use it without caffeine?<\/summary>\n<div>\n<p>Yes. The sachet is stimulant-free, and the caffeine comes in separate capsules. Use the sachet alone for evening sessions, on easy days or if you prefer to avoid stimulants, and add the capsules for long or race-pace sessions. You can also buy the powder without capsules.<\/p>\n<\/div>\n<\/details>\n<details>\n<summary>Is it allowed for tested athletes?<\/summary>\n<div>\n<p>None of the ingredients appears on the WADA Prohibited List. Caffeine was removed from the list in 2004 and is only monitored.<\/p>\n<\/div>\n<\/details>\n<details>\n<summary>Can I use it on race day?<\/summary>\n<div>\n<p>Yes, that is what it is made for, but always try it in training first, at the same time before your session as you plan to use it on race day, so you know how your body responds.<\/p>\n<\/div>\n<\/details>\n<details>\n<summary>Why should I avoid mouthwash around my serving?<\/summary>\n<div>\n<p>The nitrate in arginine nitrate is converted to nitric oxide with the help of bacteria on your tongue. Antibacterial mouthwash kills these bacteria and blunts the effect, so avoid it in the hours before and after your serving.<\/p>\n<\/div>\n<\/details>\n<details>\n<summary>Can I take it with other SCN\u2122 products?<\/summary>\n<div>\n<p>Yes, with two points to watch. Each sachet contains 25 mg of zinc, so do not combine it on the same day with other zinc supplements such as <a href=\"https:\/\/www.s-c-nutrition.com\/product\/zinc-liposmal\/\" data-wpel-link=\"external\" rel=\"noopener\">LipoZinc\u00b9\u00b2\u2075<\/a> or <a href=\"https:\/\/www.s-c-nutrition.com\/product\/maca-ashwagandha-spermidine\/\" data-wpel-link=\"external\" rel=\"noopener\">Maca 30:1 Complete Synergy<\/a>. And do not combine the NewCaff\u2122 capsules with other caffeine products, including <a href=\"https:\/\/www.s-c-nutrition.com\/product\/caffeine-endurance\/\" data-wpel-link=\"external\" rel=\"noopener\">Slow Caffeine \u2013 Pre-Endurance Caffeine<\/a>. It works well alongside your carbohydrate, electrolyte and recovery nutrition.<\/p>\n<\/div>\n<\/details>\n<details>\n<summary>Who should not take it?<\/summary>\n<div>\n<p>It is not suitable for children and adolescents under 18, or during pregnancy or breastfeeding. Speak to your doctor before use if you have a heart or blood pressure condition, or if you take any medication, in particular blood pressure medication, nitrates or erectile dysfunction medication, because arginine and nitrate can lower blood pressure, and because BioPerine\u00ae can change how some medicines are absorbed.<\/p>\n<\/div>\n<\/details>\n<h2>Warnings and Storage<\/h2>\n<div class=\"pe-warn\">\n<p><strong>Contains caffeine (450 mg per 2 NewCaff\u2122 capsules). Not recommended for children or pregnant or breastfeeding women.<\/strong> Do not exceed 2 capsules per day and avoid other sources of caffeine on the same day.<\/p>\n<p><strong>Warnings:<\/strong> Food supplements should not replace a varied and balanced diet and a healthy lifestyle. Do not exceed the stated recommended dose. Keep out of reach of young children. Not suitable for anyone under 18. Consult your doctor before use if you have a medical condition, a heart or blood pressure condition, or are taking medication. Contains 25 mg of zinc per sachet: do not combine with other supplements containing zinc.<\/p>\n<p><strong>Storage:<\/strong> Store in a cool, dry place, away from direct sunlight and out of reach of children. Each sachet is sealed for freshness: use a sachet as soon as it is opened.<\/p>\n<\/div>\n<p class=\"pe-caption\">This page is for general information only and is not a substitute for medical advice, diagnosis or treatment. If you have questions about your own health, speak to your doctor.<\/p>\n<p style=\"text-align:center;margin-top:28px\"><img decoding=\"async\" src=\"https:\/\/www.s-c-nutrition.com\/wp-content\/uploads\/2020\/05\/SCN-together-faster-longer-harder-motivational-1.gif\" alt=\"SCN\u2122 together: faster, longer, harder, endurance training motivation\" title=\"SCN\u2122 together \u2013 faster, longer, harder\" style=\"max-width:100%;height:auto;border-radius:14px\"><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Pre-Endurance Training Activator is the endurance pre-workout made for long, high-intensity sessions of up to 4 hours: 6,000 mg citrulline malate, 3,000 mg arginine AKG and 2,000 mg arginine nitrate for nitric oxide and oxygen delivery, plus grape seed extract, L-tyrosine, glucuronolactone, SenActiv\u00ae, ZincNova\u2122 and BioPerine\u00ae.<\/p>\n<ul>\n<li>NewCaff\u2122 slow-release caffeine (450 mg) for up to 4 hours, in separate capsules, so use it with or without caffeine<\/li>\n<li>Two nitric oxide pathways for blood flow from warm-up to final effort<\/li>\n<li>10 peach-flavoured sachets<\/li>\n<\/ul>","protected":false},"featured_media":9571,"template":"","meta":{"inline_featured_image":false},"product_cat":[17,23,18,39,19],"product_tag":[228],"class_list":["post-9236","product","type-product","status-publish","has-post-thumbnail","product_cat-all-products","product_cat-energy-vo2max","product_cat-specialized","product_cat-sport-line","product_cat-strength-power","product_tag-multi-buy-products","first","instock","sale","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/www.s-c-nutrition.com\/nl\/wp-json\/wp\/v2\/product\/9236","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.s-c-nutrition.com\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.s-c-nutrition.com\/nl\/wp-json\/wp\/v2\/types\/product"}],"version-history":[{"count":6,"href":"https:\/\/www.s-c-nutrition.com\/nl\/wp-json\/wp\/v2\/product\/9236\/revisions"}],"predecessor-version":[{"id":13211,"href":"https:\/\/www.s-c-nutrition.com\/nl\/wp-json\/wp\/v2\/product\/9236\/revisions\/13211"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.s-c-nutrition.com\/nl\/wp-json\/wp\/v2\/media\/9571"}],"wp:attachment":[{"href":"https:\/\/www.s-c-nutrition.com\/nl\/wp-json\/wp\/v2\/media?parent=9236"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.s-c-nutrition.com\/nl\/wp-json\/wp\/v2\/product_cat?post=9236"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.s-c-nutrition.com\/nl\/wp-json\/wp\/v2\/product_tag?post=9236"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}